13.4. 6.8. PROFILE IN PRACTICE 12.7. Genetic Conditions Affecting Fertility And it was not until the early 1900s that inherited diseases were linked to chromosomes. Clinical integration of genetic/genomic information has the potential to optimize health outcomes and lengthen patient lives. Assessment of Children with Atypical Features, Growth, or Development 9.3. 11.5. Conclusion Being able to assess clients and families with a “genetic eye” has become critical for all nurses. 11.1. 3.10. Introduction to Basic Genetics and Genomics This chapter is founded on the Essentials of Genetic and Genomic Nursing and presents genetic and genomic discoveries and applications from yesterday to today, as well as for tomorrow. Talking Glossary of Genetic Terms—National Human Genome Research Institute: www.genome.gov/glossary While I do a pedigree, I provide education and explain why I am asking the questions. 6.21. The sides of the “ladder” are formed by a backbone of sugar and phosphate molecules, and the “rungs” consist of nucleotide bases joined weakly in the middle by hydrogen bonds. She responded that she had not, but she added that since she had undergone bilateral mastectomies, it wasn’t an issue for her. I explained that although she had decreased her risk for breast cancer by having bilateral mastectomies, other cancers were also associated with BRCA mutation, ovarian cancer being the most concerning because survival rates are low, there are no good screening measures, and it usually is not detected early. Since this woman was not my patient and was not eligible for care at a military treatment facility, I had to balance educational needs and not do actual counseling. 16.6. These advances are ushering in new directions in the provision of health care and will have a significant impact on nurses and all other health care providers. Catherine Ling and Lucia Novak References, Chapter 5. Genes are pieces of DNA, and most genes contain the information for making a specific protein.
A new era of health care—called genomic health care—is rapidly advancing. Box 16-1 provides a listing of basic genetic terms and their definitions as a beginning step for nurses to become familiar with and knowledgeable about genetics and genomics. The Essentials of Genetic and Genomic Nursing was created in recognition of the important role of genetics and genomics in nursing care.
Examples of Mendelian inheritance include autosomal dominant, autosomal recessive, and sex-linked genes. Introduction The, Genetics and Genomics Educational Resources for Nurses. Genetics Education Program for Nurses—Cincinnati Children’s Hospital: www.cincinnatichildrens.org/ed/clinical/gpnf/default.htm List two new ways that genetic testing is being used in clinical practice. It pinpoints new developments in prenatal, maternity, and pediatric issues and supplies new information on genomics-based personal drug therapy, environmental susceptibilities, genetic therapies, epigenetics, and ethics. 7.4. 13.2. 16.1.
Part 1-—Genomics of Complex Cardiovascular Diseases In the words of Florence Nightingale (1859), “[T]he knowledge of nursing…of how to put the constitution in such a state as that it will have no disease, or that it can recover from disease, takes a higher place. Click to download Essentials of Genetic and Genomic Nursing: Competencies, Curricula Guidelines, and Outcome Indicators (pdf) email; facebook; linkedin; twitter; Contact ANNA. Coronary Artery Disease (or Coronary Heart Disease) All nurses, as health care providers and as citizens, are charged with understanding advances in genetics and the resultant implications on health care and social decisions. RAPID 2.4: Step 4-—Risk Assessment-—Review Data and Communicate Risk to Client/Family become familiar with and knowledgeable about genetics and genomics. Ethical Standards and Ethical Competence in Nursing
Genetic Basis for Essential Hypertension Parkland Villas The friend later contacted me to say thank you. Applications of genetics and genomics to nursing and health care will be addressed, including family history assessment, genetic screening and testing, pharmacogenetics and pharmacogenomics, and direct-to-consumer (DTC) genetic testing. References, Chapter 17.
1.11.
7.5.
Patients, families, and communities will increasingly expect all registered nurses and nurse specialists to be familiar with and use genetic and genomic information and technologies when providing care (Consensus Panel, 2008). This article series is now available as an educational resource for nurses (www.genome.gov/17515679). Risk Assessment and Interpretation 12.4. Her pathology from the bilateral oophorectomies had shown a “precancerous” lesion on one ovary, and her gynecologist said that she had been destined for full-blown ovarian cancer if the surgery had not been done when it was. 11.26. In 2003, shortly after the completion of the Human Genome Project, the American Nurses Association (ANA) published the Essentials of Genetic and Genomic Nursing: Competencies, Curricular Guidelines, and Outcome Indicators. References, Chapter 10.
The topics of prevention of genetic disease, genetic testing, and treatment are presented, including aspects of genetic counseling.
Smoking 8.8. Online Genetics Resources—National Human Genome Research Institute: www.genome.gov/10000464 Double helix—The structural arrangement of DNA, which looks something like an immensely long ladder twisted into a helix, or coil. Tags: Conceptual Foundations The Bridge to Professional Nursing Practice Introduction Published by the American Nurses Association in 2006, the Essentials of Genetic and Genomic Nursing Competencies and Curricula Guidelines were established by consensus panel to define essential genetic and genomic competencies for all nurses regardless of level of … Protein—A large complex molecule consisting of one or more chains of amino acids. Mapping and sequencing of the entire human genome was completed in 2003, after 15 years of research. Her pathology from the bilateral oophorectomies had shown a “precancerous” lesion on one ovary, and her gynecologist said that she had been destined for full-blown ovarian cancer if the surgery had not been done when it was.
References, Chapter 7. Another strategy is to have all certification exams include test items that measure the knowledge of genetic and genomic information specific to the specialty for which nurses are being certified. 6.18.
6.19. References, Chapter 8. She responded that she had not, but she added that since she had undergone bilateral mastectomies, it wasn’t an issue for her.
12.9. 11.16. Medicine and the New Genetics—Office of Science, U.S. Department of Energy: www.ornl.gov/sci/techresources/Human_Genome/medicine/medicine.shtml If you continue to use this site we will assume that you are happy with it. 16 Genetics and Genomics in Professional Nursing Dale Halsey Lea, MPH, RN, CGC, FAAN OBJECTIVES After completion of this chapter, the reader will be able to: • Define genomic health care. Mendelian inheritance—The way in which genes and traits are passed from parents to children.
The recognition that nurses did not have adequate knowledge of genetics to practice genetics health care was first documented in the nursing literature of 1979 (, Mapping and sequencing of the entire human genome was completed in 2003, after 15 years of research. Introduction Malaysia, Singapore, Allele—One of the variant forms of a gene at a particular location on a chromosome. Kathleen Calzone MSN, RN, APNG, FAAN National Institutes of Health, National Cancer Institute, Center for Cancer Research, Genetics Branch, Bethesda, Maryland Pharmacogenomics They include the incorporation of genetic and genomic technologies and information into registered nursing practice and the ability to tailor genetic and genomic information and services to clients based on their knowledge level, literacy, culture, religion, and preferred language.
Hematologic Neoplasms 9.5. The Essentials of Genetic and Genomic Nursing document includes strategies to implement the competencies into nursing practice. 15.2. Non-Mendelian Patterns of Inheritance The human genome was completely mapped and sequenced in 2003. 14.6. Edwarda M. Buda-Okreglak and Diane C. Seibert 14.1. 17.1. Functional Effects of Mutations Genetic Background
1 Tuen on Lane, Tuen Mun Quannetta T. Edwards, Ph.D., FNP-BC, WHNP-BC, AGN-BC, FAANP, Western University of Health Sciences Genomics and Cancer-Related Fatigue Also included are tests for a variety of diseases and information on pharmacogenomics, which enable health care providers to select the best drugs for treatment based on a patient's genetic makeup. Assessing Risk and the Family Health History (FHH) 8.10. Applications of genetics and genomics to nursing and health care will be addressed, including family history assessment, genetic screening and testing, pharmacogenetics and pharmacogenomics, and direct-to-consumer (DTC) genetic testing. Another of our exciting endeavors was a 2-year initiative to establish essential competencies in genetics and genomics for all nurses. 8.3. Share this:Click to share on Twitter (Opens in new window)Click to share on Facebook (Opens in new window)Click to share on Google+ (Opens in new window) This chapter is founded on the Essentials of Genetic and Genomic Nursing and presents genetic and genomic discoveries and applications from yesterday to today, as well as for tomorrow. (Consensus Panel, 2008, p. 7) The Essentials of Genetic and Genomic Nursing was developed based on several sources and resources, including (1) review of peer-reviewed published work that has reported practice-based genetic and genomic competencies, guidelines, and recommendations; (2) input from nurses who were representatives to the National Coalition for Health Professional Education in Genetics (NCHPEG) in 2005; (3) public comment from the nursing community at large; and (4) statements during open comment periods from the nurses who attended a 2-day meeting of key stakeholders held in September 2005.
Nonstructural Single Gene Cardiovascular Disorders TODAY’S GENETICS AND GENOMICS
• Define genomic health care.
Introduction Preconception Care 6.7. Chapter 1. References 62, Chapter 3. RAPID 2.3: Step 3-—Determination of Risk Probability Elements of Informed Consent for Genetic Testing Introduction The practice of clinical genetics and genomics has infiltrated nearly every area of health care. Aging, Genomics, and the Graduate Level Nurse Today's nurses must be able to "think genetically" to help individuals and families who are affected by genetic disease or contemplating genetic testing. Molecular or DNA Testing 9.1. The professional practice domain includes the following: competencies in nursing assessment (applying and integrating genetic and genomic knowledge); identification of clients who could benefit from genetic and genomic information and services as well as reliable genetic and genomic resources; referral activities; and provision of education, care, and support, such as using genetic- and genomic-based interventions and information to improve client outcomes (Consensus Panel, 2008). Since then, we have collaborated to create the core competencies in cancer genetics for advanced practice nurses, to initiate a nursing genetics and ethics study, and to publish books and articles on these topics. Jean Jenkins PhD, RN, FAAN National Institutes of Health, National Human Genome Research Institute, Bethesda, Maryland, Kathleen Calzone MSN, RN, APNG, FAAN National Institutes of Health, National Cancer Institute, Center for Cancer Research, Genetics Branch, Bethesda, Maryland.